%0 Journal Article
%A Yuxin YAN
%A Meijun HE
%A Yu LI
%A Xiaoman YUAN
%A Xuhui TAN
%A Ming CHENG
%A Kai LUO
%A Lujing LIAO
%T Whitening and Antioxidant Activities of Leaf Polysaccharide from <i>Dendrobium officinale</i>
%D 2025
%R 10.7525/j.issn.1673-5102.2025.01.012
%J Bulletin of Botanical Research
%P 111-118
%V 45
%N 1
%X <p>
	Polysaccharide from the stems and leaves of <i>Dendrobium officinale</i> was extracted and purified by water extraction and alcohol precipitation， and its hygroscopic， moisturizing， whitening and antioxidant activities were clarified， respectively. The yield of polysaccharide（L-POL） extracted and purified from <i>D. officinale</i> leaves was（13.95±0.27）% and the purity was（92.14±7.75）%. L-POL had good moisture absorption and moisture retention effects， and moisture absorption rate and moisture retention rate were（9.50±0.57）% and （25.13±0.24）%， respectively. L-POL had strong DPPH free radical scavenging ability and <i>in vitro</i> tyrosinase activity with IC<sub>50</sub> value of 2.232 and 54.930 g&sdot;L<sup>-1</sup>， respectively. L-POL with a concentration of 125 mg&sdot;L<sup>-1</sup> could significantly inhibit the synthesis of melanin by mouse melanoma cells B16 with an inhibitory rate of 36.89%. In addition， L-POL with concentrations ranging from 75-300 mg&sdot;L<sup>-1</sup> was not cytotoxic to mouse melanoma cells（cell viability of 89.33%-102.00%）. The high-purity L-POL had good antioxidant， whitening， moisture absorption and other activities， which provided a new idea for the further development and utilization of <i>D. officinale</i> resources in cosmetics or whitening functional foods.
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%U https://bbr.nefu.edu.cn/EN/10.7525/j.issn.1673-5102.2025.01.012